Oral
poliovirus vaccine (OPV) campaigns were intensified during August 2016-December 2017; since October 2016, no WPV has been detected (2).
The statement said that these countries should 'ensure that all residents and long-term visitors (four weeks) of all ages receive a dose of bivalent oral
poliovirus vaccine (bOPV) or inactivated
poliovirus vaccine (IPV) between four weeks and 12 months prior to international travel'.
The Tropis device has been shown in multiple studies to deliver a superior immune response after 2 fIPV[i],[ii] doses and uniquely enables mass-scale fractional dose
poliovirus vaccine injections[iii] at a lower total cost than intramuscular injection[iv].
In addition, in countries such as Brazil, where oral live attenuated
poliovirus vaccine (OPV) is still used, infection caused by vaccine derived polioviruses remains possible, especially in immunocompromised individuals.
The vaccinators checked the
poliovirus vaccine and organised the paperwork that would be filled with data of vaccinated children and handed over to the area in-charge on a daily basis.
Use of this inactivated
poliovirus vaccine and subsequent widespread use of the oral poliovirus, developed by Albert Sabin, led to the establishment of the Global Polio Eradication Initiative (GPEI) in 1988.
Success, in large part, has hinged on the use of trivalent, live attenuated oral
poliovirus vaccine (tOPV) throughout much of the world.
Since the World Health Assembly endorsed a plan to completely eradicate polio in 1988, the large-scale use of the attenuated oral
poliovirus vaccine (OPV) has drastically decreased the number of polio cases.
There are two types of vaccines that can prevent polio: inactivated
poliovirus vaccine (IPV) and oral
poliovirus vaccine (OPV)," said HMC's Senior Consultant in Pediatrics Dr Magda Ahmed Youssef.
The product is a four - component, combination Diptheria - Tetanus - acellular Pertussis (DTaP) and Sabin inactivated
poliovirus vaccine (sIPV) that was in Phase two of clinical development.
Lead author Dr Jacob John from Christian Medical College, India said that adding a supplementary IPV dose to children already vaccinated with oral
poliovirus vaccine (OPV) may hasten polio eradication by boosting herd immunity in endemic regions, acted as a booster to prevent international spread by travellers, and minimise the risk of polio outbreaks due to imported wildtype or vaccine-derived polioviruses.