inclusion body

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Related to inclusion body: inclusion body disease

inclusion body

An abnormal structure in a cell nucleus or cytoplasm having characteristic staining properties and usually composed of protein, occurring primarily in infectious diseases, especially viral infections such as rabies.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

inclusion body

(Pathology) pathol any of the small particles found in the nucleus and cytoplasm of cells infected with certain viruses

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

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Noun

inclusion body - any small intracellular body found within another (characteristic of certain diseases); "an inclusion in the cytoplasm of the cell"

cellular inclusion, inclusion

body - an individual 3-dimensional object that has mass and that is distinguishable from other objects; "heavenly body"

plasmid, plasmid DNA - a small cellular inclusion consisting of a ring of DNA that is not in a chromosome but is capable of autonomous replication

cancer body, Russell's body - an inclusion body found in plasma cells in cases of cancer

References in periodicals archive ?

Arimoclomol is in clinical development at Orphazyme for the treatment of Niemann-Pick disease Type C, Gaucher disease, sporadic Inclusion Body Myositis, and amyotrophic lateral sclerosis.

CytRx Corporation Highlights Arimoclomol Licensee Orphazyme A/S Prepares for Regulatory Filing of Arimoclomol in U.S. for Niemann-Pick Disease Type C

Orphazyme A/S (CPH:ORPHA.CO), a biopharmaceutical company dedicated to developing treatments for patients living with rare diseases, announced on Tuesday full enrolment of its phase II/III trial of arimoclomol for the treatment of sporadic Inclusion Body Myositis (sIBM).

Orphazyme announces full enrolment of phase II/III trial in sporadic Inclusion Body Myositis

Key words: Falconid HV-1, herpesvirus, inclusion body, hepatitis, splenitis, captive, avian, falcons, owls, pigeons

Inclusion Body Herpesvirus Hepatitis in Captive Falcons in the Middle East: A Review of Clinical and Pathologic Findings

Strategies for the recovery of active proteins through refolding of bacterial inclusion body proteins.

Cloning, Expression, and Refolding of PPE17 Protein of Mycobacterium Tuberculosis as a Promising Vaccine Candidate

119th ENMC international workshop: Trial design in adult idiopathic inflammatory myopathies, with the exception of inclusion body myositis, 10-12 October 2003, Naarden, the Netherlands.

Exploring Road of Classification Criteria for Idiopathic Inflammatory Myopathy

This study reveals the presence of two distinct groups of FAdV-4 and FAdV-11 in chickens affected with hydropericardium syndrome and inclusion body hepatitis.

Molecular Characterization and Phylogenetic Analysis of Fowl Adenoviruses Isolated from Commercial Poultry Flocks in Pakistan during 2014-15

coli) BL21 (DE3) inclusion body and refolded it using a buffer lacking a proper redox conditions.

Inclusion Body Expression and Refolding of Recombinant Bone Morphogenetic Protein-2

Inclusion body myositis (IBM) is the most common acquired myopathy in patients over 50 years [1].

IL-1[beta]-Induced Accumulation of Amyloid: Macroautophagy in Skeletal Muscle Depends on ERK

Inclusion body myositis is a rare acquired idiopathic inflammatory myopathy with the insidious onset of asymmetric and distal muscle weakness that characteristically involves the quadriceps, tibialis anterior, and forearm flexors.

Sarcoidosis: Is It a Possible Trigger of Inclusion Body Myositis?

Intracellular infection becomes initiated with infectious but metabolically inert elementary body (EB) which differentiates within the cell inside of membrane-associated vacuole (referred to as an inclusion body) into metabolically active but noninfective reticulate (RB) body [5].

Lycopene Inhibits Propagation of Chlamydia Infection

Global Markets Direct's, 'Inclusion Body Myositis (IBM) - Pipeline Review, H1 2016', provides an overview of the Inclusion Body Myositis (IBM) pipeline landscape.