excipient

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ex·cip·i·ent

(ĭk-sĭp′ē-ənt)

An inert substance used as a diluent or vehicle for a drug.

[Latin excipiēns, excipient-, present participle of excipere, to take out, exclude; see except.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

excipient

(ɪkˈsɪpɪənt)

(Pharmacology) a substance, such as sugar or gum, used to prepare a drug or drugs in a form suitable for administration

[C18: from Latin excipiēns excepting, from excipere to except]

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

ex•cip•i•ent

(ɪkˈsɪp i ənt)

n.

any pharmacologically inert substance used for combining with a drug for the desired bulk, consistency, etc.

[1745–55; < Latin excipient-, s. of excipiēns, present participle of excipere to receive, absorb, literally, to take out; see except1]

excipient

- An inactive substance that serves as the vehicle or medium for a drug; it is also the material or surface that receives the pigments in painting.

excipient

n excipiente m

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References in periodicals archive ?

A topically applied cream containing 5% vitamin C and its excipient were tested on healthy female volunteers presenting with photoaged skin on their low-neck and arms in view to evaluate efficacy and safety of such treatment.

Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo

The method is comprised of heating and melting a hydrophobic excipient and adding an antiseptic product with the melted excipient to form a liquid mixture.

Antiseptic Tampon and method of preparing it: no. 7,091,395; Jean-Bastien Pasquini and Michel Pasquini, assignors to Jean-Bastien Pasquini, Leudelange, Luxembourg. Filed 6/2/03. Issued 8/15/06

The excipients involved in the active drug formulation also have a bearing because increasing the individual dose of the drug--from twice-daily to once-daily dosing--will increase the amount of excipient to which the patient is exposed.

Patient selection critical for once-daily HAART. (Focus on Protease Inhibitors)

The reduction of 5% in these values is indicative of drug degradation, and consequently, chemical incompatibility between the drug and the excipient [22].

Development and Validation of a Chromatography Method Using Tandem UV/Charged Aerosol Detector for Simultaneous Determination of Amlodipine Besylate and Olmesartan Medoxomil: Application to Drug-Excipient Compatibility Study

We hypothesized that if amorphous excipients are added to a solid dispersion containing amorphous APIs then the probability of recrystallization of APIs will be arrested to a certain extent due to competition between the APIs and excipient.

Screening of Sacrificial Excipients for Arresting Devitrification of Itraconazole from Solid Dispersion/Itrakonazolun Kati Dispersiyondan Devitrifikasyonunu Onlemek icin Amaca Yonelik Yardimci Maddelerin Taranmasi

The new company, which will be led by Kayon Partners principals Stephen Garrow and David Vogel, will work with the UMASS tech transfer team and with established companies in the food and drug industries, to custom-develop excipient foods, which can be used along with a variety of drugs and vitamins.

Kayon teams with UMASS Food Science Group to develop new technologies

Frequent physical audits of excipients manufacturing facilities by officials from regulatory agencies lead to the imposition of substantial operating cost burdens on excipient manufacturers, thus hampering revenue growth for excipients over the forecast period.

Global Pharmaceutical Excipient Market Worth US$ 7,415.2 Mn by 2021 : PMR

The excipient has high degrees of compressibility and compactibility, and high dilution potential.

Study of the Tableting Properties of MCR, a Newly Coprocessed Cellulose-based Direct Compression Excipient/Yeni Koproses Seluloz Bazli Dogrudan Basim Yardimci Maddesi Olan MCR'nin Tabletleme Ozelliklerinin Incelenmesi

For instance, gluten is used as an excipient. But one in every 100 people in the UK has coeliac disease and can't eat gluten.

Dr Miriam Stoppard: Your pills' 'inactive' ingredients can trigger allergies; A&E records about 1.3 million visits for bad reactions to drugs every year

Eudragit FL 30 D-55 leverages Evonik's new, proprietary AEMP technology (Advanced Excipient Manufacturing Process) to combine the respective benefits of two well-established and monographed polymers including Eudragit L 30 D-55, said a statement from the company.