(32) On low power they tend to have an eosinophilic
squamoid appearance, and closer examination usually reveals ductal lumen formation.
Pyloric gland type adenoma of the gallbladder with
squamoid spindle cell metaplasia.
The tumour shows large, pale
squamoid cells, which lack keratinisation.
Occasionally there may be foci of
squamoid differentiation with horn pearls, representing intraepidermal ductal cells.
Also, a lack of
squamoid areas with intercellular bridges and/or basal like intermediate cells support a diagnosis of MASC.
The noninflamed cyst shows 2 to 3 cell layers of cuboidal to
squamoid cells adjacent to fibrous connective tissue (figure 2), rarely showing ciliated, mucous, or sebaceous cells.
Squamoid morules (also known as spindle cell metaplasia) are a syncytium of bland meningothelial-like nonkeratinizing spindle cells with a whorling pattern (Figure 1(d)).
Histologically, sebaceous carcinoma shows quite a range of differentiation, ranging from obviously multivacuolated epithelium to basaloid or
squamoid populations of cells with more occult cytoplasmic lipid content [15].
(b) Microscopic pathology of
squamoid and undifferentiated thyroid cells.
Caption: Figure 3: (a) Well-differentiated variants of adamantinoma including cords and islands of epithelial cells with a basaloid appearance, with some
squamoid differentiation, were observed in this patient.
Furthermore,
squamoid morular metaplasia has been recently described as an occasional finding in non-ITAC [3].
Papillary processes are lined by multilayered epithelium that contained both
squamoid and transitional epithelium with occasional mucocytes.