MAOI drugs

(monoamine oxidase inhibitors). a group of antidepressants. Highly effective, they require dietary precautions.

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antidepressants

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Do not combine DLPA with MAOI drugs like Anipryl, used to treat Cushing's Disease and canine cognitive dysfunction, or amitraz, an ingredient in tick collars.

Canine arthritis

Initial passage through the liver produces active metabolites from the tricyclic and atypical drugs, and inactive metabolites from the MAOI drugs ("first-pass metabolism").

The Neurobiology of Antidepressants

It is safe to combine DLPA with all other arthritis drugs, but do not combine DLPA with MAOI drugs such as Anipryl (selegiline, l-deprenyl), used in the treatment of Cushing's Disease and canine cognitive dysfunction, or amitraz (found in tick collars).

Joint decisions: many effective tools can help in the fight against canine arthritis

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